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In the context of Tsukamoto’s work, "original medicine" may symbolize:

Many of his titles use "clinical" or "original" framing to justify the specific, methodical way intimacy is portrayed. The Concept of "Original Medicine" in a Sexual Context henry+tsukamoto+original+medicine+sexual+interc

A return to a more "raw" or "original" form of human contact, free from the hyper-stylized editing of modern adult media. In the context of Tsukamoto’s work, "original medicine"

A "prescription" of specific techniques or long-form scenes designed to elicit a more profound reaction from the performers and the audience. The Evolution of Sexual Medicine and Media In the context of Tsukamoto’s work

Sekaiichi nechikkoi sex (Video 2010) - Full cast & crew - IMDb

His work often attempts to bridge the gap between performance and genuine physical response.