Before installing the VSTO 2010 Runtime, ensure your system meets these criteria:
If you are running a 64-bit version of Microsoft Office on a 64-bit Windows OS, you must have the x64 VSTO Runtime installed. microsoft visual studio 2010 tools for office runtime -x64-
A set of unmanaged DLLs used by Office applications to load the runtime and your specific solution. Why You Need the x64 Version Before installing the VSTO 2010 Runtime, ensure your
Windows 7 SP1, 8.1, 10, 11, and various Windows Server editions (2012, 2016, 2019). Before installing the VSTO 2010 Runtime
Conversely, if you have 32-bit Office installed on a 64-bit Windows system, you would actually need the x86 version of the runtime. System Requirements and Prerequisites